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Xeomin
“What is XEOMIN?”
XEOMIN is a botulinum toxin that is used to treat adults
with cervical dystonia and blepharospasm. It has been used
around the world since 2005 and was introduced to the US
market in 2010 by Merz Pharmaceuticals, LLC.
XEOMIN is a prescription medicine that is injected into
muscles and used:
To treat adults with cervical dystonia to decrease the
severity of abnormal head position and neck pain
To treat abnormal spasm of the eyelids (blepharospasm) in
adults who have had prior treatment with onabotulinumtoxinA
(Botox®)
“What is botulinum toxin?”
Botulinum toxin is a naturally occurring protein produced by
the bacteria Clostridium botulinum. Botulinum toxin type
A—the active ingredient in XEOMIN—is produced commercially
from C. botulinum serotype A.
“How does XEOMIN work?”
XEOMIN is injected into muscles to decrease their activity.
XEOMIN blocks the release of a chemical
messenger—acetylcholine—that conveys the signal from nerve
terminals and causes muscle fibers to contract. Not all
terminals are affected by botulinum toxin, so the muscles
can still contract, just less forcefully. This allows the
muscles to contract more normally.
“Are all botulinum toxin products the same?”
Not all botulinum toxin products are the same. This is
reflected in the unique names for each product. The dose of
XEOMIN may be different from other botulinum toxin products.
“How is XEOMIN made?”
In nature, C. botulinum produces the toxin in association
with accessory proteins (toxin complex). Merz takes the
toxin complex and employs a proprietary manufacturing
process that isolates the therapeutic component and removes
the accessory proteins to produce XEOMIN.
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